Poly (d/l) lactide-polycaprolactone/bioactive glass nanocomposites: assessments of in vitro bioactivity and biodegradability

The in vitro assessments suggested the essential features for bio screws applications. effects of bioactive glass nanoparticles (BG) during studies poly (D/L) lactide (PDLLA)/polycaprolactone (PCL)/BG nanocomposites (PPB) were assessed. PDLLA/PCL (PP) blends chosen as control groups. Apatite formations capabilities, weight and pH variations, alkaline phosphatase activity (ALP), MTT assay assigned different immersion times up to 6 months. XRD SEM results revealed superior apatite formation PPB simulated body fluids (SBF) compared PP. loss variation illustrated highest values related Moreover, MG-63 cells cultures determined better cell viability PP blends. Although, there are no statistically significant differences between two In addition, similar trends shown ALP where these amounts after 2 3 weeks incubation considerable comparison However, also Overall, bioactivity biodegradability confirmed that implants can be promised a proper candidate anterior cruciate ligament reconstruction screws.